It might not be absolutely confirmed, but multiple sources are reporting the character descriptions for many of the series regulars for Joss Whedon's S.H.I.E.L.D. show.
No previously-established characters make the list, but that could always be because those roles (like say, Maria Hill or Agent Sitwell) don't need to be cast. As big as Marvel is right now, it'll take a lot to get Average Joe Americans to watch a cast of unknowns.
What do you think? Is the S.H.I.E.L.D. brand strong enough to survive without some serious star power in the cast?